DAPT [208255-80-5]
HY-13027
CAS Number208255-80-5
Product group Chemicals
Estimated Purity99.62%
Molecular Weight432.46
Overview
- SupplierMedChem Express
- Product NameDAPT [208255-80-5]
- Delivery Days Customer10
- CAS Number208255-80-5
- CertificationResearch Use Only
- Estimated Purity99.62%
- Molecular FormulaC23H26F2N2O4
- Molecular Weight432.46
- Scientific DescriptionDAPT (GSI-IX) is a potent and orally active gamma-secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid-beta (Abeta) and Abeta42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment.
- SMILESFC1=CC(F)=CC(CC(N[C@H](C(N[C@H](C(OC(C)(C)C)=O)C2=CC=CC=C2)=O)C)=O)=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200