ICC/IF analysis of methanol-fixed HeLa cells using GTX50653 eIF4G antibody.
ICC/IF analysis of methanol-fixed HeLa cells using GTX50653 eIF4G antibody.
eIF4G antibody
GTX50653
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetEIF4G1
Overview
- SupplierGeneTex
- Product NameeIF4G antibody
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1981
- Target nameEIF4G1
- Target descriptioneukaryotic translation initiation factor 4 gamma 1
- Target synonymsEIF4F; EIF4G; EIF-4G1; EIF4-gamma; eIF-4-gamma 1; EIF4GI; eucaryotic translation initiation factor 4G; eukaryotic translation initiation factor 4 gamma 1; P220; PARK18
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203