Human IL-36 alpha (153a.a.) protein
ORB107763
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameHuman IL-36 alpha (153a.a.) protein
- Delivery Days Customer16
- Applications SupplierHPLC, SDS-PAGE
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionInterleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in the pathophysiology of several diseases.IL-36C, IL-36F, and IL-36G (formerly IL-1F6, IL-1F8, and IL-1F9) are IL-1 family members that signal through the IL-1 receptorfamily members IL-1Rrp2 (IL-1RL2) and IL-1RAcP. Studies showed IL-36C is mainly found in skin and lymphoid tissues, butalso in fetal brain, trachea, stomach and intestine. Notably, IL-36 alpha is the only novel IL-1 family member expressed on Tcells.Recombinant human interleukin-36 alpha (153 a.a.) contains 153 amino acids residues which is a single non-glycosylatedpolypeptide and it shares 57 - 68% a.a. sequence identity with mouse, rabbit, equine and bovine IL-36C and 27 - 57% a.a.sequence identity with other novel IL-1 family members.
- SourceE.coli
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202