Human sFasR protein
ORB107710
Product group Proteins / Signaling Molecules
Overview
- SupplierBiorbyt
- Product NameHuman sFasR protein
- Delivery Days Customer16
- Applications SupplierHPLC, SDS-PAGE
- CertificationResearch Use Only
- Estimated Purity>95%
- Scientific DescriptionFas and Fas Ligand (FasL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively.Binding of FasL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases thencleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FasL-induced apoptosis byacting as a decoy receptor that serves as a sink for FasL
- SourceE.coli
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202