Overview
- SupplierGeneTex
- Product NameIP6K1 antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.22 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Adipocyte-specific deletion of Ip6k1 reduces diet-induced obesity by enhancing AMPK-mediated thermogenesis. Zhu Q et al., 2016 Nov 1, J Clin InvestRead more
- Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain. Zhu Q et al., 2017 Jan, Mol MetabRead more
- Inositol Hexakisphosphate Kinase 1 (IP6K1) Regulates Inositol Synthesis in Mammalian Cells. Yu W et al., 2016 May 13, J Biol ChemRead more
- Inositol hexakisphosphate kinase-1 interacts with perilipin1 to modulate lipolysis. Ghoshal S et al., 2016 Sep, Int J Biochem Cell BiolRead more
- Inositol hexakisphosphate kinase-1 mediates assembly/disassembly of the CRL4-signalosome complex to regulate DNA repair and cell death. Rao F et al., 2014 Nov 11, Proc Natl Acad Sci U S ARead more
- Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. Rao F et al., 2015 Feb 10, Proc Natl Acad Sci U S ARead more
- IP6K1 Reduces Mesenchymal Stem/Stromal Cell Fitness and Potentiates High Fat Diet-Induced Skeletal Involution. Boregowda SV et al., 2017 Aug, Stem CellsRead more