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Mcl1-IN-9
T11977
Overview
- SupplierTargetMol Chemicals
- Product NameMcl1-IN-9
- Delivery Days Customer65
- CAS Number1810769-31-3
- Category SupplierChemical
- Chemical NameMcl1-IN-9
- Molecular FormulaC37H39ClN4O4
- Molecular Weight639.18
- Scientific DescriptionMcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.
- Shelf life instruction3 years
- SMILESC(CCOC1=CC(C)=C(Cl)C(C)=C1)C=2C=3C(N4C2C(=O)N(CC5=CC(C(O)=O)=CC=C5)CCC4)=C(C=CC3)C=6C(C)=NN(C)C6C
- Storage Instruction-20°
- UNSPSC12352200
References
- Lee T, et al, Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer. J Med Chem. 2019 Apr 25;62(8):3971-3988.Read more