Overview
- SupplierGeneTex
- Product NameMTHFD2 antibody [N3C3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.61 mg/ml
- IsotypeIgG
- Scientific DescriptionThis gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- MicroRNA-9 inhibition of cell proliferation and identification of novel miR-9 targets by transcriptome profiling in breast cancer cells. Selcuklu SD et al., 2012 Aug 24, J Biol ChemRead more
- Modulating redox homeostasis and cellular reprogramming through inhibited methylenetetrahydrofolate dehydrogenase 2 enzymatic activities in lung cancer. Chan CH et al., 2020 Aug 6, Aging (Albany NY)Read more