GTX86963 ICC/IF Image
NFkB p65 (acetyl Lys310) antibody
GTX86963
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
Overview
- SupplierGeneTex
- Product NameNFkB p65 (acetyl Lys310) antibody
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- HostRabbit
- IsotypeIgG
- Modification TypeAcetylated
- Scientific DescriptionNF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- ReactivityHuman, Monkey, Mouse
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Aloin Suppresses Lipopolysaccharide-Induced Inflammatory Response and Apoptosis by Inhibiting the Activation of NF-kappaB. Luo X et al., 2018 Feb 26, MoleculesRead more
- Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. Mohan M et al., 2015 Jan 1, J ImmunolRead more
- Prothymosin alpha overexpression contributes to the development of pulmonary emphysema. Su BH et al., 2013, Nat CommunRead more
- Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult. Li J et al., 2021, Front ImmunolRead more
- The phosphorylation status of T522 modulates tissue-specific functions of SIRT1 in energy metabolism in mice. Lu J et al., 2017 May, EMBO RepRead more