WB analysis of recombinant GFP-PDESA1 over-expressed cells treated with or without Atrial natriuretic peptide (ANP) using GTX14672 PDE5A antibody or GTX36930 PDE5A (phospho Ser 92) antibody. Dilution : 1:500
WB analysis of recombinant GFP-PDESA1 over-expressed cells treated with or without Atrial natriuretic peptide (ANP) using GTX14672 PDE5A antibody or GTX36930 PDE5A (phospho Ser 92) antibody. Dilution : 1:500
PDE5A (phospho Ser 92) antibody
GTX36930
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
Product group Antibodies
ReactivityBovine, Human, Mouse, Porcine, Rat, Sheep, Zebra Fish
TargetPDE5A
Overview
- SupplierGeneTex
- Product NamePDE5A (phospho Ser 92) antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody will detect only PDE5A protein that has been phosphorylated at the PKG site. Will not detect unphosphorylated PDE5A, or other PDE family members.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1-1.25 mg/ml
- ConjugateUnconjugated
- Gene ID8654
- Target namePDE5A
- Target descriptionphosphodiesterase 5A
- Target synonymsCGB-PDE; cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase; cGMP-specific 3',5'-cyclic phosphodiesterase; cGMP-specific phosphodiesterase PDE5A2; cGMP-specific phosphodiesterase type 5A; CN5A; PDE5; phosphodiesterase 5A, cGMP-specific; phosphodiesterase isozyme 5
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Scientific DescriptionThis gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- ReactivityBovine, Human, Mouse, Porcine, Rat, Sheep, Zebra Fish
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- The role of PDE5a in oocyte maturation of zebrafish. Li J et al., 2020 Jan 15, Gen Comp EndocrinolRead more
- RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity. Mukohda M et al., 2019 Mar 21, J Clin InvestRead more
- CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine. Ale-Agha N et al., 2018 Jun, PLoS BiolRead more