GTX132818 WB Image
Phospholamban (phospho Ser16) antibody
GTX132818
Product group Antibodies
Overview
- SupplierGeneTex
- Product NamePhospholamban (phospho Ser16) antibody
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.97 mg/ml
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq]
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203