PIAS1 antibody, MAb
ORB66686
Overview
- SupplierBiorbyt
- Product NamePIAS1 antibody, MAb
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB:1:1000-1:5000 WB
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID2D7
- ConjugateUnconjugated
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMouse monoclonal to PIAS1.PIAS1 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator oftranscription)] family of transcriptional modulators. PIAS1 functions as an E3 small ubiquitin-likemodifier (SUMO) ligase. It stabilizes the interaction between UBE2I and the substrate, and functionsas a SUMO-tethering factor. PIAS1 plays an important role in the transcriptional regulation ofnumerous cellular pathways, including STAT, NF-B, p53 and the steroid hormone signalingpathways. Recent studies revealed that PIAS1 is an important regulator for innate immunity,inflammatory cytokine signaling and regulatory T cell differentiation.
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203