PROTAC BRD3/BRD4-L degrader-2
HY-149948
Molecular Weight742.31
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamePROTAC BRD3/BRD4-L degrader-2
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC43H44ClN7O3
- Molecular Weight742.31
- Scientific DescriptionPROTAC BRD3/BRD4-L degrader-2 is a PROTAC molecule and can selectively degrade cellular BRD3 and BRD4-L with Ki values of 16.91 and 2.8 nM, respectively. PROTAC BRD3/BRD4-L degrader-2 also has robust antitumor activity in mouse xenograft models. PROTAC BRD3/BRD4-L degrader-2 can be used for the research of cancer[1].
- SMILESCC1=NN=C2CCC(C3=C(N12)C=CC(C4=CC=C(C=C4)CN(C)CCCCC5=C6CN(C(C6=CC=C5)=O)C7CCC(NC7=O)=O)=C3)NC8=CC=C(C=C8)Cl
- UNSPSC12352200