Ro 67-7476 [298690-60-5]
HY-100403
CAS Number298690-60-5
Product group Chemicals
Estimated Purity98.54%
Molecular Weight319.39
Overview
- SupplierMedChem Express
- Product NameRo 67-7476 [298690-60-5]
- Delivery Days Customer10
- CAS Number298690-60-5
- Estimated Purity98.54%
- Molecular FormulaC17H18FNO2S
- Molecular Weight319.39
- Scientific DescriptionRo 67-7476 is a potent positive allosteric modulator of mGluR1 and potentiates glutamate-induced calcium release in HEK293 cells expressing rat mGluR1a with an EC50 of 60.1 nM. Ro 67-7476 is a potent P-ERK1/2 agonist and activates ERK1/2 phosphorylation in the absence of exogenously added glutamate (EC50=163.3 nM).
- SMILESO=S(N1[C@H](C2=CC=C(F)C=C2)CCC1)(C3=CC=C(C)C=C3)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200