SB 203580 hydrochloride
T21675
Overview
- SupplierTargetMol Chemicals
- Product NameSB 203580 hydrochloride
- Delivery Days Customer14
- CAS Number869185-85-3
- Category SupplierChemical
- Chemical NameSB 203580 hydrochloride
- Molecular FormulaC21H17ClFN3OS
- Molecular Weight413.9
- Scientific DescriptionAdezmapimod (SB 203580) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC 50 s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38bèta2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3bèta and PKBalfa with IC 50 s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride is also an activator of autophagy and mitophagy [1].
- Shelf life instruction3 years
- SMILESCl.CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1
- Storage Instruction-20°
- UNSPSC12352200