SB 271046 hydrochloride
T4118
CAS Number209481-24-3
Product group Chemicals
Molecular Weight488.45
Overview
- SupplierTargetMol Chemicals
- Product NameSB 271046 hydrochloride
- Delivery Days Customer9
- CAS Number209481-24-3
- Category SupplierChemical
- Chemical NameSB 271046 hydrochloride
- Molecular FormulaC20H22ClN3O3S2·HCl
- Molecular Weight488.45
- Scientific DescriptionSB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant activity (EC50: 0.16 uM).
- Shelf life instruction3 years
- SMILESCC1=C(SC2=C1C=C(C=C2)Cl)S(=O)(=O)NC3=CC(=C(C=C3)OC)N4CCNCC4.Cl
- Storage Instruction-20°
- UNSPSC12352200
References
- Marcos B, et al. Br J Pharmacol. 2008 Oct;155(3):434-40.Read more