SB-284851-BT
T69815
CAS Number219769-23-0
Product group Chemicals
Molecular Weight443.52
Overview
- SupplierTargetMol Chemicals
- Product NameSB-284851-BT
- Delivery Days Customer65
- CAS Number219769-23-0
- Category SupplierChemical
- Chemical NameSB-284851-BT
- Molecular FormulaC26H26FN5O
- Molecular Weight443.52
- Scientific DescriptionSB-284851-BT is an inhibitor of BRD4/p38alfa/BRDT . SB-284851-BT inhibits BRD4-BD1 ( IC 50 =1.7 uM), p38alfa ( K d =0.47 nM), BRDT (1) ( IC 50 = 18 uM) and BRD4 (1)( IC 50 =3.7 uM). SB-284851-BT reduces IL-8 production by inhibiting p38alfa , as well as inhibiting BRD4 to down-regulates c-Myc and NF-kappaB gene pathways in cancer . SB-284851-BT can combined with the bromine domain and extra terminal (BET) .
- Shelf life instruction3 years
- SMILESO(C=1N=C(C2=C(N=CN2C3CCNCC3)C4=CC=C(F)C=C4)C=CN1)C5=CC(C)=CC(C)=C5
- Storage Instruction-20°
- UNSPSC12352200