SB-334867 free base [792173-99-0]
HY-10895A
CAS Number792173-99-0
Product group Chemicals
Estimated Purity99.33%
Molecular Weight319.32
Overview
- SupplierMedChem Express
- Product NameSB-334867 free base [792173-99-0]
- Delivery Days Customer10
- CAS Number792173-99-0
- CertificationResearch Use Only
- Estimated Purity99.33%
- Molecular FormulaC17H13N5O2
- Molecular Weight319.32
- Scientific DescriptionSB-334867 free base (SB334867A free base) is an excellent, selective and blood-brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.
- SMILESO=C(NC1=CC(OC(C)=N2)=C2C=C1)NC3=CC=NC4=CC=CN=C43
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200