SHANK2 antibody, MAb (Alkaline Phosphatase)
ORB148601
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application
Product group Antibodies
ReactivityHuman, Mouse, Rat
Overview
- SupplierBiorbyt
- Product NameSHANK2 antibody, MAb (Alkaline Phosphatase)
- Delivery Days Customer10
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application
- Applications SupplierWB (1:1000), IHC (1:1000), ICC/IF (1:100) AM, ICC, IP, WB, IHC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDN23b/6 (Formerly sold as S23b-6)
- Concentration1 mg/ml
- ConjugateAlk. Phosphatase
- HostMouse
- IsotypeIgG1
- Scientific DescriptionMouse monoclonal to SHANK2 (Alkaline Phosphatase). Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina. Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimers disease..
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C
- UNSPSC12352203