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SRI-29132
T34706
CAS Number1482305-44-1
Product group Chemicals
Molecular Weight387.52
Overview
- SupplierTargetMol Chemicals
- Product NameSRI-29132
- Delivery Days Customer65
- CAS Number1482305-44-1
- Category SupplierChemical
- Chemical NameSRI-29132
- Molecular FormulaC18H21N5OS2
- Molecular Weight387.52
- Scientific DescriptionSRI-29132 is potent; highly permeant of the blood-brain barrier; and selective for LRRK2 kinase activity, therefore effective in attenuating pro-inflammatory responses in macrophages and in rescuing neurite retraction phenotypes in neurons.
- Shelf life instruction3 years
- SMILESS(C(C(=O)N1CCCCC1)CC)C2=NN3C(=NN=C3C=C2)C4=CC=CS4
- Storage Instruction-20°
- UNSPSC12352200
References
- Liu Z, Galemmo RA Jr, Fraser KB, Moehle MS, Sen S, Volpicelli-Daley LA, DeLucas LJ, Ross LJ, Valiyaveettil J, Moukha-Chafiq O, Pathak AK, Ananthan S, Kezar H, White EL, Gupta V, Maddry JA, Suto MJ, West AB. Unique functional and structural properties of the LRRK2 protein ATP-binding pocket. J Biol Chem. 2014 Nov 21;289(47):32937-51. doi: 10.1074/jbc.M114.602318. Epub 2014 Sep 16. PubMed PMID: 25228699; PubMed Central PMCID: PMC4239640.Read more