Sunitinib (SU11248) [557795-19-4]
S7781
Overview
- SupplierSelleck Chemicals
- Product NameSunitinib (SU11248) [557795-19-4]
- Delivery Days Customer9
- CAS Number557795-19-4
- CertificationResearch Use Only
- Scientific DescriptionSunitinib (SU11248) is a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRbèta with IC50 of 80 nM and 2 nM, and also inhibits c-Kit. Sunitinib is also a dose-dependent inhibitor of the autophosphorylation activity of IRE1alfa. Sunitinib induces autophagy and apoptosis.
- UNSPSC12352200