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CXCL1 / GRO alpha antibody [N3C3]

GTX108435
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCXCL1
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Overview

  • Supplier
    GeneTex
  • Product Name
    CXCL1 / GRO alpha antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2919
  • Target name
    CXCL1
  • Target description
    C-X-C motif chemokine ligand 1
  • Target synonyms
    FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1, growth-regulated alpha protein, C-X-C motif chemokine 1, GRO-alpha(1-73), GRO1 oncogene (melanoma growth stimulating activity, alpha), GRO1 oncogene (melanoma growth-stimulating activity), MGSA alpha, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), fibroblast secretory protein, melanoma growth stimulating activity, alpha, melanoma growth stimulatory activity alpha, neutrophil-activating protein 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP09341
  • Protein Name
    Growth-regulated alpha protein
  • Scientific Description
    Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CXC chemokines are further subdivided into ELR and non-ELR types based on the presence or absence of a glu-leu-arg sequence adjacent and N terminal to the CXC motif. ELR types are chemotactic for neutrophils, while non-ELR types are chemotactic for lymphocytes.[supplied by OMIM]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Chao CC, Lee CW, Chang TM, et al. CXCL1/CXCR2 Paracrine Axis Contributes to Lung Metastasis in Osteosarcoma. Cancers (Basel). 2020,12(2). doi: 10.3390/cancers12020459
    Read this paper
  • Yuan Y, Jiang JY, Wang JM, et al. BAG3-positive pancreatic stellate cells promote migration and invasion of pancreatic ductal adenocarcinoma. J Cell Mol Med. 2019,23(8):5006-5016. doi: 10.1111/jcmm.14352
    Read this paper