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CXCL14 antibody [N3C3]

GTX108431
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCXCL14
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Overview

  • Supplier
    GeneTex
  • Product Name
    CXCL14 antibody [N3C3]
  • Delivery Days Customer
    9
  • Antibody Specificity
    Knockdown/Knockout validation was supported by references (PMID:37056937)
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.44 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9547
  • Target name
    CXCL14
  • Target description
    C-X-C motif chemokine ligand 14
  • Target synonyms
    BMAC; bolekine; BRAK; breast and kidney; chemokine (C-X-C motif) ligand 14; chemokine BRAK; CXC chemokine in breast and kidney; C-X-C motif chemokine 14; KEC; KS1; MIP-2 gamma; MIP2G; MIP-2g; NJAC; SCYB14; small inducible cytokine subfamily B (Cys-X-Cys), member 14 (BRAK); small-inducible cytokine B14; tumor-suppressing chemokine
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO95715
  • Protein Name
    C-X-C motif chemokine 14
  • Scientific Description
    This gene belongs to the cytokine gene family which encode secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC (Cys-X-Cys) subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes but not for lymphocytes, dendritic cells, neutrophils or macrophages. It has been implicated that this cytokine is involved in the homeostasis of monocyte-derived macrophages rather than in inflammation. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • C-X-C domain ligand 14-mediated stromal cell-macrophage interaction as a therapeutic target for hand dermal fibrosis.
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  • CXCL14 promotes metastasis of non-small cell lung cancer through ACKR2-depended signaling pathway.
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  • Genetic deletion of Cxcl14 in mice alters uterine NK cells. Cao Q et al., 2013 Jun 14, Biochem Biophys Res Commun
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