CXCR2, Human (His-SUMO)

MedChem Express

CXCR2, Human (His-SUMO)

10

Research Use Only

90.00

CXCR2

C-X-C motif chemokine receptor 2

CD182, CDw128b, CMKAR2, IL8R2, IL8RA, IL8RB, WHIMS2, C-X-C chemokine receptor type 2, CXC-R2, CXCR-2, CXCR2 gene for IL8 receptor type B, GRO/MGSA receptor, IL-8 receptor type 2, IL-8R B, chemokine (CXC) receptor 2, high affinity interleukin-8 receptor B, interleukin 8 receptor type 2, interleukin 8 receptor, beta, interleukin-8 receptor type B

C-X-C chemokine receptor type 2

CXCR2, the receptor for interleukin-8 (IL-8), orchestrates neutrophil activation through a G-protein-mediated phosphatidylinositol-calcium second messenger system upon IL-8 binding. Exhibiting high-affinity binding to IL-8, CXCR2 also interacts with other ligands like CXCL3, GRO/MGSA, and NAP-2. The involvement of GNAI2 underscores the intricate signaling mechanisms regulating neutrophil function through CXCR2. CXCR2 Protein, Human (His-SUMO) is the recombinant human-derived CXCR2 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

-20°C

41116100