CXCR3 antibody [HL2843]

GeneTex

CXCR3 antibody [HL2843]

7

This antibody was raised against human CXCR3 Extracellular domain.

WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Research Use Only

Monoclonal

HL2843

1 mg/ml

Unconjugated

CXCR3

C-X-C motif chemokine receptor 3

CD182; CD183; chemokine (C-X-C motif) receptor 3; chemokine receptor 3; CKR-L2; CMKAR3; C-X-C chemokine receptor type 3; G protein-coupled receptor 9; GPR9; interferon-inducible protein 10 receptor; IP-10 receptor; IP10-R; Mig receptor; MigR; Mig-R

Rabbit

IgG

C-X-C chemokine receptor type 3

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]

-20°C or -80°C,2°C to 8°C

12352203