CYC-116 [693228-63-6]

TargetMol Chemicals

CYC-116 [693228-63-6]

9

693228-63-6

Chemical

Research Use Only

CYC-116

97.59%

C18H20N6OS

368.46

CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3alpha/beta, CK2, Plk1 and SAPK2A. Phase 1.

3 years

Cc1nc(N)sc1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

-20°C

12352200