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Cyclin B1 antibody

GTX77612
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetCcnb1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cyclin B1 antibody [V152]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This is specific to a protein of 62 kD identified as cyclin B1. Cyclin B1 expression is restricted to a specific short period of the cell cycle with cyclin B1 expression detected earlier and peaking in concentration before cyclin B2 expression.
  • Application Supplier Note
    WB: 1 - 2 microg/ml. ICC/IF: 1:10 - 1:500. IHC-P: 1 - 2 microg/ml. FACS: 1:10 - 1:1000. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID268697
  • Target name
    Ccnb1
  • Target description
    cyclin B1
  • Target synonyms
    Ccnb1-r; Ccnb1-rs1; Ccnb1-rs13; CycB1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin-B1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP24860
  • Protein Name
    G2/mitotic-specific cyclin-B1
  • Scientific Description
    Essential for the control of the cell cycle at the G2/M (mitosis) transition.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Benatti P et al., 2011 Jul, Nucleic Acids Res
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  • Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint. Geley S et al., 2001 Apr 2, J Cell Biol
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  • Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero. Brandeis M et al., 1998 Apr 14, Proc Natl Acad Sci U S A
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