Cyclin E2 antibody

GeneTex

Cyclin E2 antibody

9

WB: Use at a dilution of 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CCNE2

cyclin E2

CYCE2; G1/S-specific cyclin-E2

Rabbit

IgG

G1/S-specific cyclin-E2

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203