Cyclin T2 antibody [C2C3], C-term

GeneTex

Cyclin T2 antibody [C2C3], C-term

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.51 mg/ml

Unconjugated

CCNT2

cyclin T2

cyclin T2a; cyclin T2b; cyclin-T2; CYCT2; SDS-stable vimentin-bound DNA fragment HEF42VIM22; subunit of positive elongation transcription factor b

Rabbit

IgG

Cyclin-T2

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. Two alternatively spliced transcript variants, which encode distinct isoforms, have been described. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203