Cyclopamine [4449-51-8]

MedChem Express

Cyclopamine [4449-51-8]

10

4449-51-8

Research Use Only

99.97

C27H41NO2

411.62

Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay. Cyclopamine is also a selective Smo inhibitor.

CC1=C2[C@@]([C@@]3([H])[C@]([C@@]4(C(C[C@@H](O)CC4)=CC3)C)([H])C2)([H])CC[C@@]15[C@@H]([C@@]6([H])[C@](C[C@H](C)CN6)([H])O5)C

-20°C,2°C to 8°C

12352200