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Cyclosporin H [83602-39-5]

Cyclosporin H [83602-39-5]

T21493
TargetMol Chemicals
CAS Number83602-39-5
Product group Chemicals
Estimated Purity99.87%
Molecular Weight1202.61
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Cyclosporin H
  • Delivery Days Customer
    4
  • CAS Number
    83602-39-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Cyclosporin H
  • Estimated Purity
    99.87%
  • Molecular Formula
    C62H111N11O12
  • Molecular Weight
    1202.61
  • Scientific Description
    Cyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. CsH significantly attenuated MTDs or NFP-induced inflammatory lung injury and activation of MAPK and AKT pathways. Cyclosporin H is a viral transduction enhancer which increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). When combined with Rapamycin or Prostaglandin E2 Cyclosporin H displays an additive effect. Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.
  • Shelf life instruction
    3 years
  • SMILES
    C\C=C\C[C@H](C)[C@H](O)C1N(C)C(=O)[C@@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CCCNC1=O)C(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200