![Cyclosporin H [83602-39-5] Cyclosporin H [83602-39-5]](https://www.targetmol.com/group3/M00/35/68/CgoaEWayHtGEXt3bAAAAALUl4mM763.png)
Cyclosporin H [83602-39-5]
T21493
CAS Number83602-39-5
Product group Chemicals
Estimated Purity99.87%
Molecular Weight1202.61
Overview
- SupplierTargetMol Chemicals
- Product NameCyclosporin H
- Delivery Days Customer4
- CAS Number83602-39-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameCyclosporin H
- Estimated Purity99.87%
- Molecular FormulaC62H111N11O12
- Molecular Weight1202.61
- Scientific DescriptionCyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. CsH significantly attenuated MTDs or NFP-induced inflammatory lung injury and activation of MAPK and AKT pathways. Cyclosporin H is a viral transduction enhancer which increases lentiviral transduction up to 10-fold in human cord blood-derived hematopoietic stem and progenitor cells (HSPCs). When combined with Rapamycin or Prostaglandin E2 Cyclosporin H displays an additive effect. Cyclosporin H lacks immunosuppressant activity of Cyclosporin A.
- Shelf life instruction3 years
- SMILESC\C=C\C[C@H](C)[C@H](O)C1N(C)C(=O)[C@@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)CCCNC1=O)C(C)C
- Storage Instruction-20°C
- UNSPSC12352200