CYM50308 [1345858-76-5]

MedChem Express

CYM50308 [1345858-76-5]

5

1345858-76-5

Research Use Only

98.0

C20H21F2N3O2S

405.46

CYM50308 (ML248) is a potent, selective and high affinity sphingosine-1-phosphate receptor 4 (S1P4-R) agonist with an EC50 of 56 nM. CYM50308 displays 37-fold more selective for S1P4-R than S1P5-R. CYM50308 has no activity at S1P1-R, S1P2-R and S1P3-R subtypes at concentrations up to 25 microM[1].

O=C1N(C)/C(S/C1=C\C2=C(C)N(C3=CC=C(F)C=C3F)C(C)=C2)=N/CCOC

-20°C

12352200