Cynomolgus CRTAM Protein (CRM-CM201)

KACTUS

Cynomolgus CRTAM Protein (CRM-CM201)

9

Research Use Only

>95%

Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNgamma by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.

-20°C or -80°C,-80°C

12352202