Bio-Connect

Cynomolgus IL-21R Protein (ILR-CM121)

ILR-CM121
KACTUS
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    KACTUS
  • Product Name
    Cynomolgus IL-21R Protein (ILR-CM121)
  • Delivery Days Customer
    9
  • Estimated Purity
    >95%
  • Scientific Description
    IL-21 and IL-21R were highly expressed in the lesional skin and peripheral blood of psoriasis patients. IL-21 promoted CD4 T cells proliferation and Th17 cells differentiation and inhibiting Treg cells differentiation by upregulating RORgammat expression and downregulating Foxp3 expression, with increased expression and secretion of IL-17A and IL-22.Microbial translocation and the associated immune activation during HIV-1 infection may lead to high expression levels of the IL-21R activation marker in RM B cells, a feature associated with increased apoptosis and a reduced number of these cells in the circulation.
  • Storage Instruction
    -20°C or -80°C,-80°C
  • UNSPSC
    12352202