Western Blot analysis of Human hepatocellular carcinoma tissue using CYP1A2 Polyclonal Antibody at dilution of 1:440
Western Blot analysis of Human hepatocellular carcinoma tissue using CYP1A2 Polyclonal Antibody at dilution of 1:440
CYP1A2 Polyclonal Antibody
E-AB-16677
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCYP1A2 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.3mg/ml
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzymes endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3 untranslated region.
- UNSPSC12352203