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CYP21A2 antibody [N2C3]

GTX112135
GeneTex
ApplicationsWestern Blot
Product group Antibodies
TargetCYP21A2
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Overview

  • Supplier
    GeneTex
  • Product Name
    CYP21A2 antibody [N2C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1589
  • Target name
    CYP21A2
  • Target description
    cytochrome P450 family 21 subfamily A member 2
  • Target synonyms
    21-OHase; CA21H; CAH1; CPS1; CYP21; CYP21B; cytochrome P450 XXI; cytochrome P450, family 21, subfamily A, polypeptide 2; cytochrome P450, subfamily XXIA (steroid 21-hydroxylase, congenital adrenal hyperplasia), polypeptide 2; cytochrome P450-C21B; P450c21B; steroid 21 hydroxylase; steroid 21-hydroxylase; steroid 21-monooxygenase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP08686
  • Protein Name
    Steroid 21-hydroxylase
  • Scientific Description
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Assessment of the potential of polyphenols as a CYP17 inhibitor free of adverse corticosteroid elevation. Lin CJ et al., 2014 Aug 1, Biochem Pharmacol
    Read more

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