CYP2C9 Polyclonal Antibody

Elabscience

CYP2C9 Polyclonal Antibody

12

ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

CYP2C9

cytochrome P450 family 2 subfamily C member 9

CPC9, CYP2C, CYP2C10, CYPIIC9, P450-2C9, P450IIC9, cytochrome P450 2C9, cytochrome P-450 S-mephenytoin 4-hydroxylase, cytochrome P-450MP, cytochrome P450 PB-1, cytochrome P450, family 2, subfamily C, polypeptide 9, flavoprotein-linked monooxygenase, microsomal monooxygenase, xenobiotic monooxygenase

Rabbit

IgG

Cytochrome P450 2C9

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

-20°C

41116161