Western Blot analysis of Mouse liver tissue using CYP2E1 Polyclonal Antibody at dilution of 1:250
Western Blot analysis of Mouse liver tissue using CYP2E1 Polyclonal Antibody at dilution of 1:250
CYP2E1 Polyclonal Antibody
E-AB-14909
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCYP2E1 Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA WB IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
- UNSPSC12352203