CYP51/PD-L1-IN-2

TargetMol Chemicals

CYP51/PD-L1-IN-2

999

Research Use Only

CYP51/PD-L1-IN-2

C25H23N7O3

469.5

CYP51/PD-L1-IN-2 (compound L20), a quinazoline with antifungal properties, is a potent dual inhibitor targeting both CYP51 (IC50: 0.263 microM) and PD-L1 (IC50: 0.017 microM). The compound promotes early apoptosis in the fungal cell cycle, diminishes intracellular proteins IL-2, NLRP3, and NF-kappaBp65, causes mitochondrial damage and ROS build-up, leading to fungal cell lysis and death [1].

3 years

-20°C

51202000