
WB analysis of K562 (A), SP2/0 (B), PC12 (C) whole cell lysates using GTX56292 CYP8B1 antibody.
CYP8B1 antibody
GTX56292
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCYP8B1
Overview
- SupplierGeneTex
- Product NameCYP8B1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID1582
- Target nameCYP8B1
- Target descriptioncytochrome P450 family 8 subfamily B member 1
- Target synonyms7 alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase; CP8B; CYP12; CYPVIIIB1; cytochrome P450 8B1; cytochrome P450, family 8, subfamily B, polypeptide 1; cytochrome P450, subfamily VIIIB (sterol 12-alpha-hydroxylase), polypeptide 1; sterol 12-alpha-hydroxylase
- HostRabbit
- IsotypeIgG
- Protein IDQ9UNU6
- Protein Name7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
- Scientific DescriptionThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203