Cysteine protease inhibitor-3

MedChem Express

Cysteine protease inhibitor-3

14

Research Use Only

C26H22ClF2N3O

465.92

Cysteine protease inhibitor-3 (Compound 15) is a Cysteine protease inhibitor. Cysteine protease inhibitor-3 inhibits Pf3D7, PfW2, PfFP2 and PfFP3 with IC 50 s of 0.74 microM, 1.05 microM, 3.5 microM, and 4.9 microM, respectively. Cysteine protease inhibitor-3 has anti-plasmodial efficacy against both drug-sensitive and drug-resistant parasites [1] .

OC1=CC=CC=C1C(C2=CC(F)=C(F)C=C2)N(CC3)CCN3C4=CC=NC5=CC(Cl)=CC=C54

12352200