Cytokeratin 19(A53-B/A2.26), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

Cytokeratin 19(A53-B/A2.26), CF405S conjugate, 0.1mg/mL

9

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

A53-B/A2.26

0.1 mg/ml

Other Conjugate

KRT19

keratin 19

40-kDa keratin intermediate filament; CK19; CK-19; cytokeratin 19; K19; K1CS; keratin 19, type I; keratin, type I cytoskeletal 19; keratin, type I, 40-kd

Mouse

IgG2a

Keratin, type I cytoskeletal 19

This MAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40 kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

2°C to 8°C

12352203