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Cytokeratin 20 antibody [N2C2], Internal

Research Use Only
GTX110600
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKRT20
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cytokeratin 20 antibody [N2C2], Internal
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.88 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID54474
  • Target name
    KRT20
  • Target description
    keratin 20
  • Target synonyms
    CD20; CK20; CK-20; cytokeratin 20; K20; keratin 20, type I; keratin, type I cytoskeletal 20; KRT21; protein IT
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP35900
  • Protein Name
    Keratin, type I cytoskeletal 20
  • Scientific Description
    The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Cullin 4b-RING ubiquitin ligase targets IRGM1 to regulate Wnt signaling and intestinal homeostasis. Fan Y et al., 2022 Sep, Cell Death Differ
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  • PP2A Deficiency Enhances Carcinogenesis of Lgr5+ Intestinal Stem Cells Both in Organoids and In Vivo. Yen YT et al., 2019 Dec 30, Cells
    Read more
  • Colorectal cancer derived organotypic spheroids maintain essential tissue characteristics but adapt their metabolism in culture. Rajcevic U et al., 2014, Proteome Sci
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  • The Royal Australasian College of Physicians Golden Jubilee meeting. Sydney, 8-13 May 1988. Proceedings of meetings of special societies and colleges. Abstracts., 1988 May, Aust N Z J Med
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