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Cytokeratin 5 antibody

GTX113219
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetKRT5
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cytokeratin 5 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.35 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3852
  • Target name
    KRT5
  • Target description
    keratin 5
  • Target synonyms
    58 kda cytokeratin; CK5; CK-5; cytokeratin-5; DDD; DDD1; EBS2; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; K5; keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin, type II cytoskeletal 5; KRT5A; type-II keratin Kb5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP13647
  • Protein Name
    Keratin, type II cytoskeletal 5
  • Scientific Description
    The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Retinoic acid receptor gamma activation promotes differentiation of human induced pluripotent stem cells into esophageal epithelium. Koterazawa Y et al., 2020 Aug, J Gastroenterol
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  • Knock-down of filaggrin influences the mitogen-activated protein kinases signaling pathway in normal human epidermal keratinocytes. Wang S et al., 2018 Oct, Med Sci (Paris)
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  • MAPK Pathway Involved in Epidermal Terminal Differentiation of Normal Human Epidermal Keratinocytes. Meng X et al., 2018, Open Med (Wars)
    Read more
  • MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells. Lin YC et al., 2017 Apr 12, Sci Rep
    Read more
  • LncRNA expression profile of deltaNp63alpha in cervical squamous cancers and its suppressive effects on LIF expression. Qian L et al., 2017 Aug, Cytokine
    Read more
  • Filaggrin silencing by shRNA directly impairs the skin barrier function of normal human epidermal keratinocytes and then induces an immune response. Dang NN et al., 2015 Jan, Braz J Med Biol Res
    Read more
  • Knockdown of filaggrin influences the epidermal terminal differentiation via MAPK pathway in normal human epidermal keratinocytes. Dang N et al., 2015 Feb, Mol Biol Rep
    Read more