D-4-77

MedChem Express

D-4-77

14

Research Use Only

C23H34BrN3O5

512.44

D-4-77 is a potent inhibitor of SARS-CoV-2 Mpro with an IC 50 value of 0.95 microM. D-4-77 has antiviral active with an EC 50 value of 0.49 microM. D-4-77 suppresses SARS-CoV-2 Mpro -induced antagonism of the host NF-kappaB innate immune response [1] .

CC1=CC=C(C[C@@H](C(OC)=O)NC([C@@H](NC([C@@H](NC(CBr)=O)C)=O)[C@@H](C)CC)=O)C(C)=C1

12352200