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ProductsBack/D-alpha-Hydroxyglutaric acid (disodium) [103404-90-6]

D-alpha-Hydroxyglutaric acid (disodium) [103404-90-6]

HY-100542

CAS Number103404-90-6

Product group Chemicals

Estimated Purity98.0

Molecular Weight192.08

Overview

Supplier
MedChem Express
Product Name
D-alpha-Hydroxyglutaric acid (disodium) [103404-90-6]
Delivery Days Customer
10
CAS Number
103404-90-6
Certification
Research Use Only
Estimated Purity
98.0
Molecular Formula
C5H6Na2O5
Molecular Weight
192.08
Scientific Description
D-alpha-Hydroxyglutaric acid disodium (Disodium (R)-2-hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D-2-hydroxyglutaric aciduria. D-alpha-Hydroxyglutaric acid disodium is a weak competitive antagonist of alpha-ketoglutarate (alpha-KG) and inhibits multiple alpha-KG-dependent dioxygenases with a Ki of 10.87 mM. D-alpha-Hydroxyglutaric acid disodium increases reactive oxygen species (ROS) production. D-alpha-Hydroxyglutaric acid disodium binds and inhibits ATP synthase and inhibits mTOR signaling[1][2][3][4][5].
SMILES
O=C(O[Na])[C@H](O)CCC(O[Na])=O
Storage Instruction
4°C (Powder, sealed storage, away from moisture)
UNSPSC
12352200

MSDS

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