D-Arabinopyranose [28697-53-2]

MedChem Express

D-Arabinopyranose [28697-53-2]

10

28697-53-2

Research Use Only

99.94

C5H10O5

150.13

D-Arabinopyranose is a rare aldehyde pentose, and its ring-opened form is D-arabinose (HY-N0059). D-arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-arabinose activates the ACSS2-PPARgamma/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082)[1][2][3][4].

OC1[C@H]([C@@H]([C@@H](CO1)O)O)O

-20°C,2°C to 8°C

12352200