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Chemical Structure
Chemical Structure
Chemical Structure

D-Cycloserine [68-41-7]

Research Use Only
CDX-D0356
Chemodex
CAS Number68-41-7
Product group Chemicals
Estimated Purity>98%
Molecular Weight102.09
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Packing Size
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Overview

  • Supplier
    Chemodex
  • Product Name
    D-Cycloserine [68-41-7]
  • Delivery Days Customer
    10
  • CAS Number
    68-41-7
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Non-hazardous
  • Molecular Formula
    C3H6N2O2
  • Molecular Weight
    102.09
  • Scientific Description
    Chemical. CAS: 68-41-7. Formula: C3H6N2O2. MW: 102.09. D-cycloserine (DCS) is an antibiotic, inhibiting cell-wall biosynthesis in bacteria. It is a tuberculostatic agent, that inhibits L-alanine racemase and D-alanine:D-alanine ligase, enzymes essential to peptidoglycan synthesis and bacterial cell wall formation. Formulations containing DCS have been used as second-line agents to treat drug resistant tuberculosis. A reason for limited use of this drug is the neurological side effects it causes, since it is able to penetrate into the central nervous system (CNS). DCS acts as a glutamatergic partial N-methyl-D-aspartate (NMDA) agonist. It selectively binds at the glycine-binding site of the NMDA receptor and enable the opening of the NMDA channel. DCS has the ability to improve memory retention in senescence-accelerated mice which exhibit impaired learning and memory. - D-cycloserine (DCS) is an antibiotic, inhibiting cell-wall biosynthesis in bacteria. It is a tuberculostatic agent, that inhibits L-alanine racemase and D-alanine:D-alanine ligase, enzymes essential to peptidoglycan synthesis and bacterial cell wall formation. Formulations containing DCS have been used as second-line agents to treat drug resistant tuberculosis. A reason for limited use of this drug is the neurological side effects it causes, since it is able to penetrate into the central nervous system (CNS). DCS acts as a glutamatergic partial N-methyl-D-aspartate (NMDA) agonist. It selectively binds at the glycine-binding site of the NMDA receptor and enable the opening of the NMDA channel. DCS has the ability to improve memory retention in senescence-accelerated mice which exhibit impaired learning and memory.
  • SMILES
    O=C1NOC[C@H]1N
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200