D-Isoleucine

MedChem Express

D-Isoleucine [319-78-8]

10

319-78-8

Research Use Only

99.83

C6H13NO2

131.175

D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimers disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2].

CC[C@@H](C)[C@@H](N)C(O)=O

-20°C,2°C to 8°C

12352200