D3R/MOR antagonist 1

MedChem Express

D3R/MOR antagonist 1 [3033883-15-4]

14

Research Use Only

C22H27Cl2N3O

420.38

D3R/MOR antagonist 1 (Compound 114) is a D3R/MOR antagonist (Ki: 46.5 nM and 691 nM respectively). D3R/MOR antagonist 1 has the potential to produce analgesic effects through MOR partial agonism, reduce opioid-misuse liability via D3R antagonism[1].

ClC1=C(N2CCN(CCC3(C4=NC=CC=C4)CCOCC3)CC2)C=CC=C1Cl

12131703