D3R/MOR antagonist 2

MedChem Express

D3R/MOR antagonist 2 [3033883-17-6]

14

Research Use Only

C25H31ClN2O

410.98

D3R/MOR antagonist 2 (Compound 121) is a D3R/MOR antagonist (Ki: 361 nM and 85.2 nM respectively). D3R/MOR antagonist 2 has the potential to produce analgesic effects through MOR partial agonism, reduce opioid-misuse liability via D3R antagonism[1].

ClC1=CC=C(C=C1)[C@H]2[C@@H](C2)NCCC3(C4=NC=CC=C4)CC5(CCCC5)OCC3

12131703